R. Michael Roberts, born October 23, 1940 in the United Kingdom, is an American biologist and Chancellor's Professor Emeritus of Animal Sciences and Biochemistry at the University of Missouri, known for his work on the biological signaling between an embryo and its mother in ruminant animals. He determined that uteroferrin belonged to a class of lysosomal enzymes called tartrate-resistant acid phosphatases and was first to purify, sequence and clone these enzymes in humans, and his laboratory was first to clone and characterize trophoblast interferon-tau in sheep and cattle, a signal that helps maintain pregnancy. He later identified more than one hundred genes in the aspartyl proteinase family associated with pregnancy and turned to pluripotent stem cells to study how the trophoblast, the tissue that becomes the placenta, emerges and differentiates in animals and humans.
Facts
Defining ContributionLed the research group that first cloned, identified and characterized the temporal expression of trophoblast interferon tau in sheep and cattle, clarifying how ruminant embryos signal maternal recognition of pregnancy. 1 In the Other Atlases
Sources
1. R. Michael Roberts (Wikipedia)
Wikimedia Foundationlead sentence, birth date clause
R. Michael Roberts (born October 23, 1940, in Menston, United Kingdom) is an American biologist who is the Chancellor's Professor Emeritus of Animal sciences and Biochemistry at the University of Missouri.
lead sentence, nationality clause
R. Michael Roberts (born October 23, 1940, in Menston, United Kingdom) is an American biologist who is the Chancellor's Professor Emeritus of Animal sciences and Biochemistry at the University of Missouri.
Research contributions section
Roberts' group was the first to clone, identify, and characterize the temporal expression of trophoblast interferon-t in the ruminants sheep and cattle.
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